Endocrine Abstracts

Objective: To estimate psychological rehabilitation efficiency at adolescents with T1DM.Materials and methods: Total 58 adolescents with T1DM (30m, 28f), mean age (M±σ) 15.1±2.8 years (13.00–18.00), age of T1DM manifestation 5.1±3.9 years, were provided with the PedsQL4.0 questionnaire, scales of psychological well-being (SPWB). The rehabilitation program was developed: medical unit (lessons in diabetes school and doctor’s c...

Study objective: To determine risk factors of hypoglycemic episodes among patients with type 1 diabetes mellitus (T1D) using the continuous glucose monitoring system (CGMS).Materials and methods: Total 120 female patients with T1D were examined. The 1st group was with concealed hypoglycemic episodes (n=79) that has made 66% and the 2nd group was with frank hypoglycemic episodes (n=41) that has made 31% of the total number of the examined. T...

Study objective: To study the differences of ghrelin basal levels (BG) among people with abdominal obesity.Materials and methods: One hundred and twenty-two patients aged 35–55 with obesity and 28 practically healthy persons (control group) were examined. The groups were identical in the sex and age, obesity. The BG levels in serum were measured by the immune-enzyme method with «DRG International» reagents.Results: A...

Aims: Thyroid status disturbances are not rare among DKD patients. It is known that the genesis of anemia in DKD has a multifactorial nature, and the combination of DKD and anemia significantly impairs quality of life. In addition, anemia in diabetic patients with DKD occurs earlier and tends to be more severe compared with CKD patients without diabetes. The purpose of the study was to investigate potential relationship between thyroid status and iron metabolism profile in pat...

Background: Diabetic nephropathy (DN) is a serious complication of diabetes associated with increased risk of mortality, cardiovascular and renal outcomes. Diagnostic markers to detect DN at early stage are important as early intervention can slow loss of kidney function and improve patient outcomes. The aim of our study was to evaluate the role of serum cystatin C (CysC) for early detection of kidney damages in patients with type 2 diabetes mellitus (DT2).<p class="abstex...

Objective: Assessment of the frequency of hypoglycaemic episodes during daily monitoring of glucose in the subcutaneous water of women and men with type 1 diabetes mellitus.Methods: The study of daily dynamics of glucose has been performed with continuous glucose monitoring system (CGMS) Medtronik MINIMED company (USA). The study involved 162 patients with type 1 diabetes mellitus. The patients were divided into two groups: group 1 – women with regu...

Purpose: To evaluate the possible risk factors for depression development in type 1 diabetes mellitus (DM 1).Methods: 163 patients with DM 1. Depression was determined by the hospital anxiety and depression scale (HADS). Common factors of risk depression development were assessed by questionnaire survey according to a specially designed questionnaire. The levels of HbA1c and homocysteine (HC) serum were determined.Results: Depressi...

Secondary hyperparathyroidism is highly prevalent in patients with end-stage chronic kidney disease (CKD). Optimal range of PTH level for this cohort of patients is still controversial. The aim of the study was to use a neural network algorithm to determine the optimal point value and confidence interval for the average PTH value for patients with end-stage chronic kidney disease to maintain bone metabolism.The study included 190 patients with end-stage ...

Aims: Thyroid function changes are common endocrine disturbance among patients with chronic kidney disease (CKD), including those receiving renal replacement therapy (RRT). The purpose of the study was to study the effect of RRT on thyroid function in patients with type 1 diabetes (T1D).Materials and methods: Thyroid hormone examination was performed before and after hemodialysis procedures (HD) in 9 patients with T1D (3 men and 6 women). Mean age was 41...

Aim: To define the frequency of diabetic retinopathy course in type1 diabetes mellitus (T1DM) patients with and depression; to study the relation between depression and diabetic retinopathy severity.Materials and methods: One hundred and thirty-three T1DM patients aged 40.27±12.17 years (56 males and 77 females) without exacerbation of chronic and acute inflammatory diseases and verified mental disorders were included into the study. The duration of...